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The effects of dietary 9‐ trans ,12‐ rans ‐octadecadienoate on composition and fatty acids of rat lungs
Author(s) -
Yu P.,
Mai J.,
Kinsella J. E.
Publication year - 1980
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534426
Subject(s) - lipidology , clinical chemistry , arachidonic acid , chemistry , composition (language) , food science , oleic acid , biochemistry , polyunsaturated fatty acid , fatty acid , enzyme , medicine , endocrinology , biology , linguistics , philosophy
Dietary trans,trans ‐linoleate ( trans 18∶2), when fed to rats in increasing amounts, caused a reduction in lung weights, particularly at very high dietary concentrations. The fatty acids of the phospholipids and triglycerides were altered. The percentage of oleic and arachidonic acid decreased as dietary trans 18∶2 was increased. Eicosatrienoic acid (20∶3) appeared in the phospholipids of lungs from rats receiving 100% dietary trans 18∶2, but its concentration was much lower than in lungs from rats on an essential fatty acid deficient diet, indicating that trans 18∶2 inhibited the enzymes synthesizing 20∶3.