Premium
The influence of linoleic acid intake on electron transport system components
Author(s) -
Abuirmeileh N. M.,
Elson C. E.
Publication year - 1980
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534416
Subject(s) - cytochrome c oxidase , mitochondrion , electron transport chain , cytochrome , cytochrome c , cytochrome b , biochemistry , chemistry , antimycin a , linoleic acid , cytochrome c1 , alternative oxidase , biology , coenzyme q – cytochrome c reductase , fatty acid , enzyme , mitochondrial dna , gene
Groups of young rats were fed a basal diet with beef tallow (BT) or corn oil (CO) added to provide 4 or 19% energy as linoleic acid. Mitochondria isolated from the livers of the rats fed the CO contained a significantly lower concentration of b‐type cytochrome and significantly higher concentrations of cytochromes c, c 1 and aa 3 . Cytochrome c oxidase activity also was elevated. The spectral characteristics of the b‐type cytochrome varied between the 2 groups. The mitochondria from the rats fed CO contained relatively more of the cytochrome b‐558 component whereas mitochondria from the BT group contained more of the cytochrome b‐562 component. The classical antimycin A inhibition of electron transport between cytochromes b and c 1 was partially bypassed in mitochondria with the more fluid membrane. The activation energy for cytochrome c oxidase in mitochondria from this group was significantly higher. These differences may be traced to the physical characteristics of the inner mitochondrial membrane.