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Fatty acids of sphingomyelin from amniotic fluid of normal and diabetic pregnancies
Author(s) -
Kokatnur Mohan,
Brooks Vicki,
Plauche Warren C.
Publication year - 1985
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534236
Subject(s) - sphingomyelin , amniotic fluid , lecithin , chemistry , behenic acid , fatty acid , arachidic acid , oleic acid , medicine , palmitic acid , chromatography , endocrinology , biochemistry , cholesterol , biology , pregnancy , fetus , genetics
Amniotic fluid collected from 14 normal and 11 diabetic patients was analyzed for phospholipids, and separated sphingomyelin and lecithin fractions were further studied for their fatty acid composition by gas liquid chromatography. Notable differences in percent fatty acid composition of sphingomyelin were observed for palmitic (16∶0; diabetic < normal), oleic (18∶1; diabetic > normal), behenic (22∶0; diabetic < normal) and arachidic acid (20∶0; absent in diabetics) in the specimens studied. Notable differences were not observed in fatty acids from lecithin fraction. Fatty acid composition of sphingomyelin from amniotic fluid is similar to fatty acid distribution in sphingomyelin from serum and erythrocyte and suggests maternal origin of the lipid.