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Dinosterol in model membranes: Fluorescence polarization studies
Author(s) -
Harel Zvi,
Djerassi Carl
Publication year - 1980
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02534022
Subject(s) - microviscosity , dinoflagellate , membrane , fluorescence anisotropy , sterol , fluorescence , lipidology , biology , biochemistry , clinical chemistry , chemistry , biophysics , botany , cholesterol , physics , quantum mechanics
The interaction between the phospholipids of Crypthecodinium cohnii , a heterotropic marine dinoflagellate, and its major sterol dinosterol was studied using a fluorescence polarization technique. Compared to cholesterol, dinosterol is less soluble in model membranes and as effective in increasing the microviscosity. These results indicate that the unique side chain of dinosterol does not play a special role in terms of complementary interaction with the phospholipids of this organism.