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Metabolism of 2,4‐ 3 H‐14α‐methyl‐5α‐ergost‐8‐enol and 2,4‐ 3 H‐5α‐ergosta‐8,14‐dienol in Ochromonas malhamensis
Author(s) -
Adler John H.,
Patterson G. W.
Publication year - 1976
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02532878
Subject(s) - lipidology , metabolism , clinical chemistry , chemistry , enol , organic chemistry , biochemistry , catalysis
Tritium‐labeled 14α‐methyl‐5α‐ergost‐8‐enol and 5α‐ergosta‐8,14‐dienol were converted to brassicasterol and poriferasterol in Ochromonas malhamensis . This indicates that the organism can rearrange these sterol structures so that they contain the naturally occurring 5(6) double bond, and suggests that O. malhamensis is able to introduce a 24(28) double bond into a nine‐carbon saturated side chain which is alkylated to produce a C‐29 sterol.