Detection of lithocholic acid in multiple sclerosis brain tissue | Zendy

Mujtaba Naqvi S. H. | Zendy; Ramsey Robert B. | Zendy; Nicholas H. J. | Zendy

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Detection of lithocholic acid in multiple sclerosis brain tissue

Author(s) -

Mujtaba Naqvi S. H.,

Ramsey Robert B.,

Nicholas H. J.

Publication year - 1970

Publication title -

lipids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.601

H-Index - 120

eISSN - 1558-9307

pISSN - 0024-4201

DOI - 10.1007/bf02532752

Subject(s) - lithocholic acid , multiple sclerosis , lipidology , autopsy , human brain , pathology , clinical chemistry , coronal plane , medicine , chemistry , biology , anatomy , biochemistry , immunology , neuroscience , bile acid

By methods previously employed for detecting lithocholic acid in brains of guinea pigs afflicted with experimental allergic encephalitis, the same acid was detected in a coronal specimen of human brain obtained on autopsy of a multiple sclerosis patient. The specimen contained several well‐defined demyelinated plaque areas. No lithocholic acid was detected in a somewhat larger coronal specimen of normal human brain.

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