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Effect of dietary saturated fatty acids and linoleic acid upon the structures of triglycerides in rabbit tissues
Author(s) -
Christie W. W.,
Moore J. H.,
Gottenbos J. J.
Publication year - 1974
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02532693
Subject(s) - myristic acid , adipose tissue , linoleic acid , lipidology , palmitic acid , lauric acid , food science , stearic acid , clinical chemistry , fatty acid , chemistry , biochemistry , composition (language) , biology , cholesterol , organic chemistry , linguistics , philosophy
Five groups of rabbits were given a diet supplemented with safflower seed oil and safflower seed oil partially replaced by lauric, myristic, palmitic, and stearic acids respectively. After 10 weeks, plasma samples were taken from the animals in the fasted and nonfasted state; the animals then were killed, and the livers and samples of adipose tissue were removed. Lipids were extracted from the tissues, then separated into classes; and the fatty acid composition of each class was determined. In addition, the triglycerides were isolated and the structures determined by stereospecific analysis. There were marked differences in the compositions and structures of the triglycerides in the plasma from fasted and nonfasted animals. Feeding specific dietary fatty acids also greatly changed the metabolism of linoleic acid by the animals. The results are discussed in terms of the biosynthesis of triglycerides in plasma, liver, and adipose tissue.