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Preparation of fully deuterated fatty acids by simple method
Author(s) -
Hsiao C. Y. Y.,
Ottaway C. A.,
Wetlaufer D. B.
Publication year - 1974
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02532618
Subject(s) - lipidology , simple (philosophy) , clinical chemistry , chemistry , chromatography , organic chemistry , biochemistry , philosophy , epistemology
An economical, simple, efficient system of deuterating saturated fatty acids at atmospheric pressure has been developed. Exchange is carried out between fatty acids and deuterium gas over palladium on charcoal catalyst at 195 C. The method was applied to even membered fatty acids containing from 6–14 carbon atoms. The method yielded perdeuterated fatty acids of high isotopic purity with no evidence of other reaction products.