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Effect of androgens on serum lipids and lipoproteins
Author(s) -
Solyom Antal
Publication year - 1972
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02532595
Subject(s) - lipidology , anabolism , clinical chemistry , endocrinology , medicine , chemistry , apolipoprotein b , lipid metabolism , metabolism , blood lipids , plasma lipoprotein , mechanism of action , cholesterol , biochemistry , lipoprotein , biology , in vitro
The effects of androgens on lipid transport and metabolism have been reviewed. These effects are probably independent of the androgenic and anabolic activities of the androgens, although the molecular mechanism of action is still not known. Presumably the lowering by androgens of the concentrations of serum lipids and lipoproteins could be the consequence possibly of a primary, inhibitory effect on the synthesis of apolipoprotein A. In addition the role of increased lipolytic activities in plasma and of effects on intermediatry metabolism has been considered.