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Identification and quantitation of cholanoic acids in hepatic and extra‐hepatic tissues of rat
Author(s) -
Oh Suk Yon,
Dupont Jacqueline
Publication year - 1975
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02532456
Subject(s) - lipidology , clinical chemistry , chemistry , identification (biology) , biochemistry , chromatography , medicine , biology , botany
Tissues of rats were examined for the presence of cholanoic acids. Quantitation of extraction, deconjugation, and isolation were verified by use of radioactive standards. Identification was made by thin layer and gas liquid chromatographic comparison to standards and mass spectrometry. All tissues examined were found to contain several conjugated cholanoic acids. Liver contained primarily cholic acid and peripheral tissues primarily dihydroxy compounds, mainly hyodeoxycholic acid.