Premium
Human placental lipid metabolism. III. Synthesis and hydrolysis of phospholipids
Author(s) -
Robertson Alex,
Sprecher Howard
Publication year - 1967
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02531854
Subject(s) - clinical chemistry , lipidology , lipid metabolism , hydrolysis , metabolism , biochemistry , chemistry , enzyme , placenta , biology , fetus , pregnancy , genetics
Both diacyl GPC (glycerylphosphorylcholine) and diacyl GPE (glycerylphosphorylethanolamine) are synthesized in human placental tissue from their respective monoacyl precursors. The origin of the monacyl phosphatides is apparently not the result of placental phosphatide acyl‐hydrolase activity. The most likely source is maternal serum. The declining level of 1‐acyl GPC in maternal serum is not attributable to lysophosphatide acylhydrolase activity and is probably explained by placental utilization for the synthesis of diacyl GPC.