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The occurrence of diastereomers of phytanic and pristanic acids and their determination by gas‐liquid chromatography
Author(s) -
Ackman R. G.,
Hansen R. P.
Publication year - 1967
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02531848
Subject(s) - phytol , diastereomer , chromatography , chemistry , phytanic acid , gas chromatography , organic chemistry , biochemistry , peroxisome , gene
The methyl esters of phytanic (3,7,11,15‐tetramethylhexadecanoic) and pristanic (2,6,10,14‐tetramethylpentadecanoic) acids derived from phytol each can be resolved into two diastereomers by gas‐liquid chromatography on an efficient open‐tubular, gas‐liquid chromatographic column with a polyester coating. Authentic D,D,D isomers prepared from the lipids of bacterium H. cutirubrum gave only one peak. In mammals the D,D,D isomers usually predominate, but in marine life the L,D,D isomers apparently are the principal forms. The origin and metabolic roles of the diastercomers are discussed.