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The incorporation of 14 C‐glycerol into different species of diglycerides and triglycerides in rat liver slices
Author(s) -
Hill Edward E.,
Lands William E. M.,
Slakey Sister P. M.
Publication year - 1968
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02531279
Subject(s) - diglyceride , glycerol , glyceride , double bond , lipidology , chemistry , biosynthesis , clinical chemistry , biochemistry , triglyceride , molecule , monoglyceride , stereochemistry , organic chemistry , cholesterol , enzyme , fatty acid
The relative rates of de novo synthesis of species of diglycerides and triglycerides from 14 C‐glycerol were examined in rat liver slices. Diglycerides containing one or two double bonds per molecule and triglycerides containing four or more double bonds per molecule represented 70% and 60% respectively of the newly synthesized diglycerides and triglycerides. The newly synthesized triglycerides were more unsaturated than the endogenous triglycerides. Our results suggest that a nonrandom synthesis of species of diglycerides occurred followed by an almost random utilization of the various diglyceride species for the biosynthesis of triglycerides.