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Incorporation of U‐ 14 C‐leucine into the serum lipoproteins and proteins of partially hepatectomized rats
Author(s) -
Narayan K. Ananth
Publication year - 1970
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02531116
Subject(s) - lipidology , clinical chemistry , medicine , leucine , endocrinology , lipoprotein , chemistry , high density lipoprotein , biochemistry , cholesterol , biology , amino acid
The incorporation of U‐ 14 C‐leucine into five classes of serum lipoproteins and into lipoprotein‐free serum proteins was investigated in partially hepatectomized, sham operated and normal rats. The serum concentration of very low density lipoprotein and the predominant subfraction of high density lipoprotein (HDL 2 ) was considerably reduced in partially hepatectomized rats as compared with both normal and sham operated rats. The incorporation of U‐ 14 C‐leucine into HDL 2 of partially hepatectomized rats was only one third and one fourth of that observed with normal and sham operated rats, respectively. On the other hand, the incorporation of the label into low density lipoproteins and into serum proteins was slightly greater in partially hepatectomized rats as compared with normal rats. In sham operated animals, the incorporation into most fractions was considerably greater than those observed with lobectomized and normal rats.