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Circum‐annual changes in triglyceride fatty acids of bat brown adipose tissue
Author(s) -
Paulsrud John R.,
Dryer R. L.
Publication year - 1968
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/bf02530936
Subject(s) - brown adipose tissue , adipose tissue , oleic acid , triglyceride , palmitic acid , chemistry , linoleic acid , fatty acid , food science , clinical chemistry , biochemistry , medicine , endocrinology , zoology , biology , cholesterol
A circum‐annual study of the fatty acids of brown adipose tissue triglycerides of Eptesicus fuscus has demonstrated a rhythmic pattern of change. This is seen as a reciprocal shift of the levels of oleic and linoleic acids. Oleic acid levels are lower during the summer months and higher in the winter months. Levels of palmitic and linoleic acids reach maximal values in midsummer and fall significantly during the winter. Homogenates of brown adipose tissue produce more 14 CO 2 from 1‐ 14 C‐palmitic acid than from 1‐ 14 C‐oleic acid when incubated at temperatures below 20C. The formation of 14 CO 2 from either substrate was maximal in the neighborhood of 30C, and the temperature effect was enhanced by stimulation with DL‐carnitine. It is proposed that the rhythmic change in brown adipose tissue triglyceride composition is a reflection of the different rates of fatty acid oxidation and the absence of normal food intake for extended periods of time.