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Assignment of the human peroxisomal palmitoyl‐CoA oxidase gene to chromosome 17q23‐qter by PCR technique
Author(s) -
Moghrabi N. N.,
Dawson D. B.,
Bennett M. J.
Publication year - 1995
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/bf02436760
Subject(s) - peroxisome , gene , oxidase test , human genetics , genetics , biology , chromosome , peroxisomal disorder , enzyme , microbiology and biotechnology , biochemistry
Summary Human peroxisomal palmitoyl‐CoA oxidase plays a pivotal role in the β‐oxidation of fatty acids. Its importance is reflected by the severity of the disease associated with its deficiency in man. The gene was previously mapped to chromosome 17q25 with a FISH technique and is now confirmed using a PCR technique.