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Kidney metastasis from gallbladder cancer
Author(s) -
Ikoma Akira,
Tanaka Koki,
Hamada Nobuo,
Taira Akira,
Miyawaki Itaru,
Matsukida Sumika
Publication year - 1996
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/bf02349801
Subject(s) - medicine , gallbladder , metastasis , adenocarcinoma , cholecystectomy , kidney , cancer , primary tumor , wedge resection , lymph , gallbladder cancer , lymph node , lymphadenectomy , pathology , radiology , surgery , resection
A case of kidney metastasis from primary gallbladder cancer is presented. Five years after operation for gallbladder cancer, a 73‐year‐old woman exhibited hematuria. Imaging disclosed a 5×4cm solid mass in the right kidney and enlarged lymph nodes behind the inferior vena cava adjacent to the right renal vein. The right kidney and adjacent tissues, including retroperitoneum and regional lymph nodes, were resected en bloc. The renal tumor was diagnosed as a metastasis from the primary adenocarcinoma of the gallbladder, based on histological similarities, absence of other primary adenocarcinoma, and fluctuations in CA19‐9 levels during the progress and after the resection of the metastatic tumor. The initial operation had been an extended cholecystectomy with wedge resection of the liver bed, plus regional lymphadenectomy. The excised gallbladder had a 2.3 ×1.2cm nodular tumor in the fundus. Histological examination indicated the gallbladder tumor to be a moderately differentiated tubular adenocarcinoma invading the subserosal layer. Mild lymphatic invasion was recognized in the gallbladder wall, although lymph node metastasis was negative. We believe this patient represents the first case of kidney metastasis from gallbladder cancer. The mode of spread of the gallbladder cancer to the kidney appeared to be lymphogenous.