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High‐Porosity expanded polytetrafluoroethylene grafts with omentum wrap for portal vein replacement: Intermediate results
Author(s) -
Nishibe Toshiya,
Ohkashiwa Hideki,
Satoh Yoshiaki,
Iwashiro Nozomu,
Watanabe Satoshi,
Katoh Hiroyuki,
Okuda Yasuhiro,
Tanabe Tatsuzo
Publication year - 1996
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/bf02349795
Subject(s) - medicine , greater omentum , surgery , polytetrafluoroethylene , vein , materials science , composite material
The purpose of this study was to examine the intermediate (6‐month) patency and healing characteristics of high‐porosity expanded polytetrafluoroethylene (ePTFE) grafts with and without omentum wrap in a dog portal vein replacement model, compared with short‐term (1‐month) results. The grafts, either wrapped by omentum or not, were placed as portal vein replacements in 22 mongrel dogs. After 1 and 6 months, the grafts were retrieved and examined for patency and subjected to pathology study. Although the short‐term patency rate in all grafts was 100%, regardless of the presence or absence of omentum wrap, the intermediate patency of high‐porosity ePTFE without omentum wrap was very poor (20%). On the other hand, high‐porosity ePTFE with omentum wrap had an intermediate patency rate of 100%. At 6 months, the high‐porosity ePTFE grafts with omentum wrap were completely healed. The pseudointima was entirely replaced by thin fibrous tissue, with complete endothelial‐like cell coverage throughout the graft. This result suggests that high‐porosity ePTFE with omentum wrap could be a suitable prosthetic alternative to autogenous vein graft in portal vein reconstruction.