Ascorbic acid: An unstable ninhydrin‐positive urinary constituent running with valine in a commonly used screening system | Zendy

Pollitt R. J. | Zendy; Sandhu B. | Zendy

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Ascorbic acid: An unstable ninhydrin‐positive urinary constituent running with valine in a commonly used screening system

Author(s) -

Pollitt R. J.,

Sandhu B.

Publication year - 1980

Publication title -

journal of inherited metabolic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.462

H-Index - 102

eISSN - 1573-2665

pISSN - 0141-8955

DOI - 10.1007/bf02312517

Subject(s) - ninhydrin , ascorbic acid , valine , urine , confusion , chemistry , chromatography , urinary system , biochemistry , amino acid , medicine , food science , psychology , psychoanalysis

Large amounts of ascorbic acid occur occasionally in the urine of children being investigated for possible inherited metabolic disease and may give a positive ninhydrin reaction after thin‐layer chromatography. As this compound is unstable in urine and runs with valine in a solvent system commonly used for preliminary screening, it is a possible source of confusion.

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