Premium
Ascorbic acid: An unstable ninhydrin‐positive urinary constituent running with valine in a commonly used screening system
Author(s) -
Pollitt R. J.,
Sandhu B.
Publication year - 1980
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/bf02312517
Subject(s) - ninhydrin , ascorbic acid , valine , urine , confusion , chemistry , chromatography , urinary system , biochemistry , amino acid , medicine , food science , psychology , psychoanalysis
Abstract Large amounts of ascorbic acid occur occasionally in the urine of children being investigated for possible inherited metabolic disease and may give a positive ninhydrin reaction after thin‐layer chromatography. As this compound is unstable in urine and runs with valine in a solvent system commonly used for preliminary screening, it is a possible source of confusion.