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Analytical procedures for diagnosis of trace element disorders
Author(s) -
Fell G. S.
Publication year - 1983
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/bf01811316
Subject(s) - trace (psycholinguistics) , trace element , gastrointestinal tract , medicine , computational biology , bioinformatics , computer science , pathology , biology , chemistry , philosophy , linguistics , organic chemistry
Trace element levels in tissues show changes in various diseases including inborn errors of metabolism. Such changes may be primary or secondary due to stress or diseases of the liver and gastrointestinal tract. Measurement of trace elements in these cases may be essential both for diagnostic and therapeutic purposes. Trace element measurements can also be useful in other areas of clinical interest including nutrition, toxicity and therapy with inorganic pharmaceutical agents. The available techniques for measuring trace elements in tissues are summarized and the various problems of each are discussed.