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Investigation of paediatric liver disease
Author(s) -
Kelly D.,
Green A.
Publication year - 1991
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/bf01797923
Subject(s) - medicine , presentation (obstetrics) , disease , liver disease , pathology , hematology , pediatrics , bioinformatics , biology , surgery
Summary The investigation of children with liver disease falls into two categories: the investigation of the cholestatic baby and the investigation of the older child (over 2 years) with hepatomegaly. The approach to investigation is directed by the clinical features and employs many different investigational methods including biochemistry, haematology, radiology, electrophysiology and histology. As the clinical presentation of many diseases is similar, it is appropriate to perform a variety of first‐line tests, proceeding to more complex investigations only as indicated.