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Partial splenic embolization in patients with liver cirrhosis and hepatocellular carcinoma: Effects on portal hemodynamics
Author(s) -
Yamashiro Kazuhiro,
Mukaiya Mitsuhiro,
Kimura Hiromichi,
Katsuramaki Tadashi,
Sasaki Kazuaki,
Denno Ryuichi,
Hirata Koichi
Publication year - 1994
Publication title -
journal of hepato‐biliary‐pancreatic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.63
H-Index - 60
eISSN - 1868-6982
pISSN - 0944-1166
DOI - 10.1007/bf01222244
Subject(s) - medicine , hepatocellular carcinoma , cirrhosis , indocyanine green , gastroenterology , portal venous pressure , liver function , embolization , splenic vein , hemodynamics , portal hypertension , perioperative , varices , radiology , surgery
Partial splenic embolization (PSE) was performed on patients with liver cirrhosis to control hypersplenism and gastroesophageal varices. In this study, we evaluated the effects of PSE on the portal hemodynamics and hepatic function of 17 cirrhotic patients with hepatocellular carcinoma. The mean splenic volume and the peak platelet count increased significantly and the splenic vein pressure decreased significantly after PSE. However, the portal blood flow did not change. Changes in the 15‐min retention rate of indocyanine green and the arterial ketone body ratio were not significant, but the redox tolerance index increased from 0.24 ± 0.28 × 10 −2 to 0.59 ± 0.35 × 10 −2 . These results suggest that PSE may reduce perioperative risks in cirrhotic patients with hepatocellular carcinoma who are candidates for hepatic resection.