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Ceroid, lipofuscin and the ceroid‐lipofuscinoses (Batten Disease)
Author(s) -
Jolly R. D.,
Dalefield R. R.,
Palmer D. N.
Publication year - 1993
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1007/bf00710265
Subject(s) - lipofuscin , batten disease , biology , biochemistry , gene
Conclusion The similar histochemical, fluorescent and ultrastructural appearance of some lipofuscins and the pigment of Batten disease imply some underlying common chemical feature. The similar chloroform—methanol solubility of the protein subunit c in Batten disease and the specific proteins accumulated in thyroid lipofuscin imply that disordered or delayed catabolism of hydrophobic protein may be that common feature.