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Bohr effect induced by CO2 and fixed acid at various levels of O2 saturation in duck blood
Author(s) -
Michaël Meyer,
J Holle,
Peter Scheid
Publication year - 1978
Publication title -
pflügers archiv - european journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.428
H-Index - 129
eISSN - 0365-267X
pISSN - 0031-6768
DOI - 10.1007/bf00584956
Subject(s) - bohr model , saturation (graph theory) , bohr effect , chemistry , mathematics , medicine , physics , quantum mechanics , hemoglobin , oxygen–haemoglobin dissociation curve , combinatorics
The Bohr factor, phi = delta log Po2/deltapH, was determined at various levels of hemoglobin O2 saturation (SO2) in fresh whole blood of the duck. Plasma pH was varied by either changing PCO2 of the blood at constant base excess (CO2 Bohr factor, phiCO2) or by addition of NaHCO3 and HCl at constant PCO2 (fixed acid BOHR factor, phiAH). No differences were found between phiCO2 and phiAH at SO2 levels between 20 and 85%, and there was no saturation dependence of the Bohr factor, its average value being -0.44. It is concluded that in whole blood of this bird species CO2 exerts no direct effect on the O2 affinity of hemoglobin.

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