Open AccessQ-banding of human chromosomes after BUdR and BCdR treatment
Author(s) -
Erica M. Bühler,
T. Tsuchimoto,
György Kosztolányi,
Linda P. Jurik
Publication year - 1976
Publication title -
human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.351
H-Index - 137
eISSN - 1432-1203
pISSN - 0340-6717
DOI - 10.1007/bf00270860
Subject(s) - biology , g banding , giemsa stain , karyotype , genetics , human genetics , metabolic disease , microbiology and biotechnology , chromosome , endocrinology , gene
Two different Q patterns were found in BUdR and BCdR treated chromosomes of human lymphocyte cultures: X-type pattern, in which Giemsa and quinacrine banding both are reversed; Y-type pattern, in which Q-banding remains conventional in spite of reverse G-banding. Possible mechanisms of these findings are discussed.