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VACUOLATION IN T‐TUBULES AS A MODEL FOR TUBULAR‐VESICULAR TRANSFORMATIONS IN BIOMEMBRANE SYSTEMS
Author(s) -
Krolenko Sergei A.,
Lucy Jack A.
Publication year - 2002
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.2002.0945
Subject(s) - membrane , biophysics , biological membrane , model system , chemistry , microbiology and biotechnology , skeletal muscle , biology , anatomy , biochemistry , computational biology
This review outlines the basic properties of T‐tubules in skeletal muscle cells, and the factors that govern reversible vacuolation in T‐tubules under experimental conditions. Comparable membranous transformations, involving the plasma membrane or occurring intracellularly, in non‐muscle cells are then considered. Finally, the mechanisms of similar transformations in various model membrane systems are discussed. In view of the similarities between reversible vacuolation in the T‐system and membrane transformations occurring in a variety of non‐muscle cells, it is suggested that reversible vacuolation in T‐tubules may be regarded as a general model for tubular‐vesicular transformations in biomembranes.