Premium
HIGH RESOLUTION SCANNING FORCE MICROSCOPY OF CARDIAC MYOCYTES
Author(s) -
Davis Jason J.,
Hill H. Allen O.,
Powell Trevor
Publication year - 2001
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.2001.0813
Subject(s) - sarcolemma , endoplasmic reticulum , scanning force microscopy , myocyte , atomic force microscopy , microscopy , resolution (logic) , biophysics , cardiac myocyte , high resolution , scanning ion conductance microscopy , chemistry , microbiology and biotechnology , anatomy , biology , materials science , nanotechnology , physics , computer science , optics , scanning confocal electron microscopy , artificial intelligence , remote sensing , geology
The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be expected of the external sarcolemma, but also resolve sub‐surface features, including the striated pattern of the contractile proteins and their associated sarcoplasmic reticulum and mitochondria.