Premium
AUTOMATED DETECTION OF MORPHOLOGICAL ALTERATIONS DURING APOPTOSIS
Author(s) -
Lertworasirikul Thawatchai,
Bunyaratvej Ahd,
Kubota Fumio
Publication year - 2000
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.2000.0560
Subject(s) - apoptosis , computational biology , biology , microbiology and biotechnology , biochemistry
A convenient means of measuring apoptosis is described using an automated analyzer (MF‐1; Sysmex), which normally provides rapid measurement of malarial parasites. By means of this MF‐1 procedure, apoptotic cells exhibited characteristic changes of light scatter (size) and fluorescence (DNA content) relating to cell shrinkage and nuclear fragmentation of apoptosis.