DECREASED DENSITIES OF INTRAMEMBRANOUS PARTICLES AND CYTOCHEMICALLY DETECTABLE CHOLESTEROL IN MICROVILLI OF STARVED RAT ENTEROCYTES | Zendy

WAHEED A. A. | Zendy; TOYAMA Y. | Zendy; YASUZUMI F. | Zendy; GUPTA P. D. | Zendy

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DECREASED DENSITIES OF INTRAMEMBRANOUS PARTICLES AND CYTOCHEMICALLY DETECTABLE CHOLESTEROL IN MICROVILLI OF STARVED RAT ENTEROCYTES

Author(s) -

WAHEED A. A.,

TOYAMA Y.,

YASUZUMI F.,

GUPTA P. D.

Publication year - 1998

Publication title -

cell biology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.932

H-Index - 77

eISSN - 1095-8355

pISSN - 1065-6995

DOI - 10.1006/cbir.1998.0227

Subject(s) - filipin , intramembranous ossification , sterol , cholesterol , brush border , microbiology and biotechnology , biology , membrane fluidity , membrane , chemistry , biochemistry , biophysics , vesicle

The densities of intramembranous particles (IMPs) and of sterol complexes induced by treatment of filipin were studied by freeze‐fracture replication of intact intestine and/or isolated brush border membranes (BBM) of well‐fed and starved rats. The density of IMPs and filipin‐sterol complexes (FSCs) decrease considerably during starvation. Biochemical estimations show a decrease in the levels of cholesterol and proteins with respect to phospholipids during starvation which is in agreement with morphological findings. It is suggested that these changes may play a role in regulating membrane fluidity which in turn affects absorption of nutrients through BBM.

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