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A RAPID BIOASSAY TO DETECT MYCOTOXINS USING A MELANIN PRECURSOR OVERPRODUCER MUTANT OF THE CILIATE TETRAHYMENA THERMOPHILA
Author(s) -
GONZÁLEZ ANA MARTÍN,
BENÍTEZ LAURA,
SOTO TRINIDAD,
LECEA RODRIGUEZ JOSEFINA,
GUTÍERREZ JUAN CARLOS
Publication year - 1997
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.1997.0134
Subject(s) - diacetoxyscirpenol , patulin , mutant , bioassay , tetrahymena , mycotoxin , biology , citrinin , toxin , melanin , chemistry , microbiology and biotechnology , trichothecene , biochemistry , genetics , food science , gene
Four different mycotoxins (patulin, T‐2 toxin, diacetoxyscirpenol and roquefortine) were used to study growth inhibitory effects on a melanin precursor overproducer mutant of the ciliate Tetrahymena thermophila This strain is especially sensitive to diacetoxyscirpenol and T‐2 toxin. The secretion capacity of melanin precursors into the culture medium by this mutant and its biosensor capacity are very useful characteristics to elaborate a rapid bioassay to detect some specific mycotoxins.