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GLUCOSE STRONGLY STIMULATES RATE OF THE RRNA SYNTHESIS IN EHRLICH ASCITES CARCINOMA CELLS
Author(s) -
Buzhurina I. M.,
Chernaya N. G.,
Panov M. A.
Publication year - 1994
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.1994.1095
Subject(s) - ehrlich ascites carcinoma , intracellular , ribosomal rna , stimulation , ascites , carcinoma , chemistry , biochemistry , biology , medicine , endocrinology , gene , in vitro , genetics
A change in glucose concentration in an Ehrlich ascites carcinoma cell suspension from 0.1 mM to 20 mM causes a more than 50‐fold stimulation of the rate of ribosomal RNA synthesis. Such an effect occurs without any dramatic effect on the rate of protein synthesis in cells. This process parallels a decrease in intracellular pH which may be a reason of Na + /H + ‐antiport activation.