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Phagocytic activity of Dictyostelium amoebae treated with an organochlorine pesticide.
Author(s) -
Gayatri R.,
Chatterjee S.
Publication year - 1993
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1006/cbir.1993.1071
Subject(s) - pesticide , organochlorine pesticide , chemistry , environmental chemistry , dictyostelium , toxicology , microbiology and biotechnology , zoology , biology , biochemistry , ecology , gene
The effect of an organochlorine pesticide benzene hexachloride (containing α, β, γ and δ isomers) on the phagocytic activity of the vegetative cells of Dictyostelium discoideum was investigated. Benzene hexachloride (BHC) at concentrations of 60 ppm and above inhibited the phagocytic activity as revealed by 3 H‐labelled E. coli uptake. The BHC treated cells also showed smaller and delayed plaque formation. Interactions of lipophilic pesticide with the hydrophobic cell surface presumably alters the receptor mediated phagocytosis of Dictyostelium amoebae.