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Pedigree analysis by computer simulation
Author(s) -
MacCluer Jean W.,
VandeBerg John L.,
Read Bruce,
Ryder Oliver A.
Publication year - 1986
Publication title -
zoo biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.5
H-Index - 54
eISSN - 1098-2361
pISSN - 0733-3188
DOI - 10.1002/zoo.1430050209
Subject(s) - biology , mendelian inheritance , equus , allele , evolutionary biology , genotype , genetics , zoology , gene
Computer simulation is a valuable tool in the genetic management of captive populations. It can be used to assess the extent of genetic variability in a colony, to predict the risk of future loss of variability, or to identify likely ancestral sources of traits of interest. “Gene dropping” is a simulation procedure in which hypothetical alleles are assigned to each colony founder, and a genotype is created for each descendant by Mendelian segregation of parental alleles. The gene dropping method is applied to analyses of four populations: (1) a colony of small South American marsupials, Monodelphis domestica ; (2) Speke's gazelles, Gazella spekei ; (3) Przewalski's horses, Equus przewalskii ; and (4) American Standardbred horses.