Cyclometalated Iridium(III) and Rhodium(III) Complexes Containing Naphthyridine Ligands: Synthesis, Characterization and Biological Studies

The synthesis, crystal structure, and biological activity of new bis‐cyclometalated compounds [ M (ptpy) 2 (4‐chloro‐2‐methyl‐1,8‐naphthyridine)]PF 6 [ M = Rh ( 1 ); M = Ir ( 2 ); ptpy = 2‐( p ‐tolyl)pyridinato] and [ M (ptpy) 2 (2‐methyl‐1,8‐naphthyridine)]PF 6 [ M = Rh ( 3 ); M = Ir ( 4 )] are described. The new compounds were prepared by the reaction of [{ M (μ‐Cl)(ptpy) 2 } 2 ] ( M = Rh, Ir) with the corresponding naphthyridine ligands. The molecular structures of compounds 1 , 3 , and 4 were confirmed by single‐crystal X‐ray diffraction studies.