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Syntheses and Structures of Organotin(IV) Thioesters of N ‐Phthaloylamino Acids
Author(s) -
Fard Zohreh Hassanzadeh,
Müller Christian,
Dehnen Stefanie
Publication year - 2008
Publication title -
zeitschrift für anorganische und allgemeine chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.354
H-Index - 66
eISSN - 1521-3749
pISSN - 0044-2313
DOI - 10.1002/zaac.200800195
Subject(s) - thio , chemistry , stereochemistry , medicinal chemistry
Five organotin(IV) thioesters of N ‐phthaloyl amino acids with the general formulae R 3 SnL (R = Me, Ph) and n Bu 2 SnL 2 were synthesized with L = N ‐phthaloyl‐thioalanine and N ‐phthaloyl‐thioleucine. The structures of trimethyltin(IV) N ‐phthaloyl‐ thio leucinate ( 1 ), trimethyltin(IV) N ‐phthaloyl‐ thio alaninate ( 2 ), triphenyltin(IV) N ‐phthaloyl‐ thio leucinate ( 3 ), triphenyltin(IV) N ‐phthaloyl‐ thio alaninate ( 4 ), and di‐ n ‐butyltin(IV) di‐ N ‐phthaloyl‐ thio alaninate ( 5 ) were characterized by means of X‐ray diffractometry. Quantumchemical investigations served to clarify several structural peculiarities of the isolated compounds.