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Non‐racemic Tin(IV) Complexes Containing P ‐chirogenic Phosphinomethylphenolate Ligands
Author(s) -
Müller Gerhard,
Brand Jörg
Publication year - 2005
Publication title -
zeitschrift für anorganische und allgemeine chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.354
H-Index - 66
eISSN - 1521-3749
pISSN - 0044-2313
DOI - 10.1002/zaac.200500163
Subject(s) - tin , chemistry , phosphine , racemization , ligand (biochemistry) , tetracoordinate , intramolecular force , medicinal chemistry , stereochemistry , coordination geometry , oxygen atom , lithium (medication) , crystallography , catalysis , organic chemistry , molecule , receptor , hydrogen bond , medicine , computer graphics (images) , biochemistry , computer science , planar , endocrinology
The chiral Sn IV complexes L*SnMe 2 Cl ( 5 ) and L*SnMe 2 H ( 6 ) containing the P ‐chirogenic o ‐[( t ‐butyl)(phenyl)phosphinomethyl]phenolate ligand (L*) have been synthesized via the respective lithium complex [LiL*] 4 ( 4 ). The synthesis and structure of 4 are described. The stereochemical course of the ligand synthesis was monitored by chiral HPLC and single crystal structure analysis on suitable intermediates. The tin atom in 5 is pentacoordinate by intramolecular phosphine coordination whereas 6 contains tetracoordinate tin without phosphine coordination. Slow racemization of 5 at 100 °C afforded 5‐rac while oxidation with elemental oxygen led under retention of configuration at phosphorus to the phosphinoxide complex o ‐[(tBu)(Ph)P*(O)CH 2 ]C 6 H 4 OSnMe 2 Cl ( 7 ) with P‐O coordination to tin. The compounds 5 , 5‐rac , and 7 were also characterized by X‐ray diffraction.