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π‐Facial Selectivity in the Formation of Tricarbonylchromium(0) Complexes of Estra‐1, 3, 5(10), 6‐tetraenes
Author(s) -
Dongol Krishna Gopal,
Melo e Silva M. Cristina,
Matsubara Kouki,
Matsumoto Taisuke,
Mataka Shuntaro,
Thiemann Thies
Publication year - 2003
Publication title -
zeitschrift für anorganische und allgemeine chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.354
H-Index - 66
eISSN - 1521-3749
pISSN - 0044-2313
DOI - 10.1002/zaac.200300017
Subject(s) - chemistry , steric effects , moiety , selectivity , stereoselectivity , stereochemistry , medicinal chemistry , catalysis , organic chemistry
The preparation of two η 6 ‐estra‐1, 3, 5(10), 6‐tetraene tricarbonylchromium complexes 4 and 6 are described. In both cases only one stereoisomer can be isolated, in contrast to other estrane‐tricarbonylchromium complexes, where complexations are non‐stereoselective. X‐ray crystal structural analysis of 4 discloses that only the more sterically hindered β ‐facial isomer is formed. It is assumed that the 6, 7‐olefinic moiety exerts a directive influence on the complexation.