Isolation of a  Candida glabrata  homologue of  RAP1 , a regulator of transcription and telomere function in  Saccharomyces cerevisiae | Zendy

Haw Robin | Zendy; Devi Yarragudi Aruna | Zendy; Uemura Hiroshi | Zendy

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Isolation of a Candida glabrata homologue of RAP1 , a regulator of transcription and telomere function in Saccharomyces cerevisiae

Author(s) -

Haw Robin,

Devi Yarragudi Aruna,

Uemura Hiroshi

Publication year - 2001

Publication title -

yeast

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.923

H-Index - 102

eISSN - 1097-0061

pISSN - 0749-503X

DOI - 10.1002/yea.775

Subject(s) - biology , saccharomyces cerevisiae , candida glabrata , telomere , open reading frame , gene , genetics , telomere binding protein , gene silencing , mutant , transcription factor , peptide sequence , dna binding protein , candida albicans

To study the function of RAP1 , an essential gene involved in the regulation of transcriptional activation, silencing and the telomere function in Saccharomyces cerevisiae , we isolated a Candida glabrata gene that complements the growth defect of a S. cerevisiae rap1 conditional mutant. The DNA sequence of the cloned gene, which we designated CgRAP1 , predicted a 2064 bp open reading frame encoding a 687 amino acid protein with an overall identity of 65% and a similarity of 78% to Rap1p from S. cerevisiae . Its DDBJ/EMBL/GenBank Accession No. is AB055655. Copyright © 2001 John Wiley & Sons, Ltd.

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