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Yeast sequencing reports. Gcs1 , a gene encoding γ‐glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe
Author(s) -
Coblenz Anke,
Wolf Klaus
Publication year - 1995
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320111207
Subject(s) - biology , complementation , schizosaccharomyces pombe , gene , genetics , amino acid , intron , schizosaccharomyces , mutant , saccharomyces cerevisiae , homologous chromosome , yeast , microbiology and biotechnology
Abstract By complementation of a mutant resistant to N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative γ‐glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids. The gsc1 sequence appears in the EMBL database under Accession Number X 85017.