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II . Yeast sequencing reports. Analysis of a 70kb region on the right arm of yeast chromosome II
Author(s) -
Mannhaupt Gertrud,
Stucka Rolf,
Ehnle Susanne,
Vetter Irene,
Feldmann Horst
Publication year - 1994
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320101014
Subject(s) - biology , accession number (library science) , gene , genetics , intergenic region , yeast , nucleic acid sequence , coding region , chromosome , dna sequencing , sequence analysis , sequence (biology) , open reading frame , computational biology , saccharomyces cerevisiae , genbank , genome , peptide sequence
In the framework of the EC programme for sequencing yeast chromosome II, we have determined the nucleotide sequence of a 70 kb region. Subsequent analysis revealed 35 open reading frames, 14 of which correspond to known yeast genes. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 1.98 kb. Coding regions occupy 75% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes. The complete nucleotide sequence of the 70 kb segment as depicted in Figure 1 has been deposited in the EMBL data library under Accession Number X78993.