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Physical constitution of ribosomal genes in common strains of Saccharomyces cerevisiae
Author(s) -
Rustchenko Elena P.,
Sherman Fred
Publication year - 1994
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320100904
Subject(s) - biology , saccharomyces cerevisiae , strain (injury) , genetics , chromosome , ribosomal dna , gene , restriction enzyme , ribosomal rna , phylogenetics , anatomy
Several recent investigations, employing restriction endonucleases that do not cleave within rDNA units, revealed that a number of laboratory strains of Saccharomyces cerevisiae apparently contain a single tandem array of approximately 50 to 200 rDNA units on each chromosome XII homolog. The number of these rDNA units varies from strain to strain, among subclones of the same strain, and after different conditions of growth. In contrast, the commonly‐used strain S288C and its derivatives contain two clusters on each chromosome XII homolog. Although the two clusters are stably maintained, the number of rDNA units within each cluster can vary as in strains with single clusters.