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V . Yeast mapping reports. The MAG1 3‐methladenine DNA glycosylase gene is closely linked to the SPT15 TATA‐binding TFIID gene on chromosome V‐R in Saccharomyces cerevisiae
Author(s) -
Xiao Wei,
Penugonde Vasu,
Rank Gerald H.
Publication year - 1994
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320100513
Subject(s) - biology , gene , genetics , microbiology and biotechnology , dna , saccharomyces cerevisiae
The MAG1 gene encodes a 3‐methyladenine DNA glycosylase, which is involved in DNA alkylation repair in Saccharomyces cerevisiae . The mag1 mutant is deficient in 3‐methyladenine DNA glycosylase activity and shows enhanced sensitivity to several monofunctional alkylating agents. MAG1 is allelic to MMS5 . This gene has been previously located on chromosome V by chromosomal hybridization. We present physical and genetic mapping data here showing that the MAG1 gene is located on chromosome V‐R, proximal to and about 10 kilobase pairs away from the SPT15 gene coding for the yeast TATA‐binding protein TFIID.