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DNA sequence analysis of a 17 kb fragment of yeast chromosome XI physically localizes the MRB1 gene and reveals eight new open reading frames, including a homologue of the KIN1/KIN2 and SNF1 protein kinases
Author(s) -
Pallier Chantal,
Valens Michèle,
Puzos Valérie,
Fukuhara Hiroshi,
Chéret Geneviève,
Sor Frédéric,
BolotinFukuhara Monique
Publication year - 1993
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320091016
Subject(s) - biology , genetics , cosmid , open reading frame , gene , nucleic acid sequence , saccharomyces cerevisiae , sequence (biology) , microbiology and biotechnology , peptide sequence
We report in this paper the sequence of a part of chromosome XI of Saccharomyces cerevisiae . This 17 kbp nucleotide sequence represents the right half of cosmid pUKG151 and contains nine open reading frames, YKL453, 450, 449, 448, 445, 443, 442, 441 and the 5′ part of YKL440. YKL440 was previously identified as the MBR1 gene and plays a role in mitochondrial biogenesis. YKL443 is a homologue of the yeast serine‐rich protein ( SRP1 ), while YKL453 presents strong homologies with the KIN1/KIN2/SNF1 kinase family. It must be pointed out that the size of this gene is well above average for yeast.