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The complete sequence of a 6794 bp segment located on the right arm of chromosome II of Saccharomyces cerevisiae . Finding of a putative dUTPase in a yeast
Author(s) -
Doig Francois,
Biteau Nicolas,
Aigle Michel,
Crouzet Marc
Publication year - 1993
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320091014
Subject(s) - biology , saccharomyces cerevisiae , open reading frame , homology (biology) , genetics , gene , nucleic acid sequence , chromosome , yeast , peptide sequence , microbiology and biotechnology
The DNA sequence of a 6794 bp fragment located at about 100 kb from the right telomere of chromosome II from Saccharomyces cerevisiae has been determined. Sequence analysis reveals five open reading frames. One is the ARO4 gene encoding the 3‐deoxy‐ D ‐arabinoheptulosonate 7‐phosphate synthase. Another presents strong homology with the S5 ribosomal protein from bacteria. The open reading frame YBR1705 shows significant homology with dUTPase, suggesting for the first time the existence of such an enzyme in S. cerevisiae .