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Sequence and function analysis of a 4·3 kb fragment of Saccharomyces cerevisiae chromosome II including three open reading frames
Author(s) -
SchaaffGerstenschläger Ine,
Baur Axel,
Boles Eckhard,
Zimmermann Friedrich K.
Publication year - 1993
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320090811
Subject(s) - biology , open reading frame , saccharomyces cerevisiae , genetics , mutant , nucleic acid sequence , fragment (logic) , chromosome , sequence (biology) , yeast , sequence analysis , microbiology and biotechnology , dna , peptide sequence , gene , algorithm , mathematics
The nucleotide sequence of a fragment of 4337 base pairs of Saccharomyces cerevisiae chromosome II has been determined. The sequence contains three open reading frames, one of them being incomplete. Deletion analysis showed that YBR12.31 is essential for yeast growth, while deletion mutants of YBR12.32 and YBR12.33 are viable. YBR12.33 is identical to SMY2 , isolated as a suppressor of a myo2 mutant (Lillie, S.H. and Brown, S.S., unpublished, EMBL M90654).