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The complete sequence of a 19,482 bp segment located on the right arm of Chromosome II from Saccharomyces cerevisiae
Author(s) -
Doig Francois,
Biteau Nicolas,
Crouzet Marc,
Aigle Michel
Publication year - 1993
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320090210
Subject(s) - biology , homology (biology) , orfs , genetics , open reading frame , saccharomyces cerevisiae , bacillus subtilis , gene , nucleic acid sequence , complete sequence , peptide sequence , microbiology and biotechnology , chromosome , genome , bacteria
We report here the sequence of a 19,482 bp DNA segment of chromosome II of Saccharomyces cerevisiae . The fragment contains 16 open reading frames (ORFs) covering 74% of the sequence. Four predicted products present homology with known proteins. The ORF YBR1732 exhibits a strong homology to serine hydroxymethyl transferase; the best score is 53·1% identity in 458 amino acids overlap with the serine hydroxymethyl transferase from rabbit liver. YBR1724, which shows homology with riboflavin synthase of Bacillus subtilis , is probably the RIB5 gene implied in riboflavine synthesis and mapped in this region. YBR1733 is homologous to rab protein and YBR1728 is presumably a GTPase activating protein.