A putative serine/threonine protein kinase gene on chromosome III of  Saccharomyces cerevisiae | Zendy

Wilson Cathal | Zendy; Frontali Laura | Zendy; Bergantino Elisabetta | Zendy; Carignani Giovanna | Zendy; Lanfranchi Gerolamo | Zendy; Valle Giorgio | Zendy

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A putative serine/threonine protein kinase gene on chromosome III of Saccharomyces cerevisiae

Author(s) -

Wilson Cathal,

Frontali Laura,

Bergantino Elisabetta,

Carignani Giovanna,

Lanfranchi Gerolamo,

Valle Giorgio

Publication year - 1992

Publication title -

yeast

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.923

H-Index - 102

eISSN - 1097-0061

pISSN - 0749-503X

DOI - 10.1002/yea.320080108

Subject(s) - biology , subfamily , gene , genetics , c raf , saccharomyces cerevisiae , homology (biology) , protein kinase a , cyclin dependent kinase 7 , map2k7 , nucleic acid sequence , microbiology and biotechnology , biochemistry , cyclin dependent kinase 2 , kinase

We have sequenced a gene on chromosome III of Saccharomyces cerevisiae which codes for a putative serine/threonine protein kinase of 726 amino acids (calculated molecular weight 82 kDa). We have called this gene KIN82 . The amino acid sequence of KIN82 is most similar to the cyclic nucleotide‐dependent protein kinase subfamily and the protein kinase C subfamily. Gene disruption of KIN82 did not produce any phenotype when tested under a variety of conditons. Reduced stringency hybridizations revealed the presence of another genomic sequence with high homology to the carboxy‐terminal catalytic domain of KIN82 .

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