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A putative serine/threonine protein kinase gene on chromosome III of Saccharomyces cerevisiae
Author(s) -
Wilson Cathal,
Frontali Laura,
Bergantino Elisabetta,
Carignani Giovanna,
Lanfranchi Gerolamo,
Valle Giorgio
Publication year - 1992
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320080108
Subject(s) - biology , subfamily , gene , genetics , c raf , saccharomyces cerevisiae , homology (biology) , protein kinase a , cyclin dependent kinase 7 , map2k7 , nucleic acid sequence , microbiology and biotechnology , biochemistry , cyclin dependent kinase 2 , kinase
We have sequenced a gene on chromosome III of Saccharomyces cerevisiae which codes for a putative serine/threonine protein kinase of 726 amino acids (calculated molecular weight 82 kDa). We have called this gene KIN82 . The amino acid sequence of KIN82 is most similar to the cyclic nucleotide‐dependent protein kinase subfamily and the protein kinase C subfamily. Gene disruption of KIN82 did not produce any phenotype when tested under a variety of conditons. Reduced stringency hybridizations revealed the presence of another genomic sequence with high homology to the carboxy‐terminal catalytic domain of KIN82 .