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A genomic sequence of the Schizosaccharomyces pombe 16 kDa vacuolar H + ‐ATPase
Author(s) -
Toyama Reiko,
Goldstein David J.,
Schlegel Richard,
Dhar Ravi
Publication year - 1991
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320070911
Subject(s) - schizosaccharomyces pombe , biology , schizosaccharomyces , genomic dna , homology (biology) , exon , gene , peptide sequence , nucleic acid sequence , microbiology and biotechnology , rna splicing , biochemistry , amino acid , atpase , genetics , rna , saccharomyces cerevisiae , enzyme
We have isolated the gene encoding the 16 kDa vacuolar H + ‐ATPase from Schizosaccharomyces pombe . On the basis of RNA splicing signals and amino acid sequence homology with other 16 kDa H + ‐ATPases, the genomic DNA sequence indicated the 16 kDa protein is encoded by five exons. The C‐terminal 50 amino acids has more than 90% homology with vacuolar H + ‐ATPases of mammalian cells.