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The start gene CDC28 and the genetic stability of yeast
Author(s) -
Devin A. B.,
Prosvirova T. Yu.,
Peshekhonov V. T.,
Chepurnaya O. V.,
Smirnova M. E.,
Koltovaya N. A.,
Troitskaya E. N.,
Arman I. P.
Publication year - 1990
Publication title -
yeast
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320060308
Subject(s) - biology , yeast , cyclin dependent kinase 1 , gene , mitosis , genetics , saccharomyces cerevisiae , chromatin , mutation , cell cycle , recombinant dna , microbiology and biotechnology
The cdc28 ‐srm mutation in Saccheromyces cerevisiae decreases spontaneous and induced mitochondrial rhomutability and the mitotic stability of native chromosomes and recombinant circular minichromosomes. The effects of cdc28 ‐srm on the genetic stability of cells support the hypothesis that links cell cycle regulation in yeast to changes in chromatin organization dependent on the start gene CDC28 (Hayles and Nurse, 1986).