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Yeast centromeres
Author(s) -
FitzgeraldHayes Molly
Publication year - 1987
Publication title -
yeast
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 102
eISSN - 1097-0061
pISSN - 0749-503X
DOI - 10.1002/yea.320030306
Subject(s) - biology , citation , centromere , library science , genetics , computer science , gene , chromosome
Significant progress has been made toward understanding the roles played by conserved centromere DNA sequences in both mitotic and meiotic chromosome segregation. We are just beginning to formulate a picture of what a yeast kinetochore actually looks like and what components other than CEN DNA are necessary for function. In the next few years some of the genes encoding structural components of the kinetochore, and perhaps some involved in regulation of kinetochore function, will be cloned. Work is already in progress to isolate and characterize the proteins necessary for the assembly, maintenance and function of this amazing biological structure.